CockTail 2 oz (Dr. Klinghardt’s Lyme Cocktail)

by BioPure
Sold out
SKU CockTail 2 oz (Dr. Klinghardt’s Lyme Cocktail)

Dr. Klinghardt’s newest herbal blend is a compilation of several of the most commonly used products in his signature Lyme Cocktail. It is a proprietary blend of BioPure’s LipoSorb, Quintessence, Artemis, Brazilian Green Propolis, Cistus Incanus, Stevia and Astragalus. This product contains organic grain alcohol.

BioPure’s newest herbal blend is a compilation of several of the most commonly used products in Dr. Klinghardt’s evolving Lyme Cocktail. It is a proprietary blend of BioPure’s LipoSorb, Quintessence, Artemis, Brazilian Green Propolis, Cistus Incanus, Stevia  Cilantro and Astragalus.

**Quintessence consists of: Andrographis, Smilax, Japanese Knotweed, Red Root and Stephania.

BioPure’s Cocktail is a unique blend of seven of our products, combined to give the immune system a powerful boost. We have included LipoSorbTM, BioPure’s proprietary form of the important lipid phosphatidylcholine, sourced from purified soy lecithin and encapsulated in an easily absorbable, hydrophyilic vesicle. Phosphatidylcholine is abundant throughout the human body, serving critical roles as both a structural and functional component of cell membranes. It is involved in cell membrane transport, detoxification, healthy cholesterol metabolism, proper nervous system function, fetal development, immune system response, and more. For more detailed information and references regarding LipoSorbTM, please see

The other six ingredients in BioPure’s Cocktail are herbal extracts with long histories of use in traditional and homeopathic medicine, including the following:

Artemisinin, from the sweet wormwood plant (Artemisia annua), is a bioactive alkaloid found in Artemis. Artemisinin may help support our immune system. For more details, see

Astragalus, from the root of a leguminous herb sometimes called milkvetch (Astragalus membranaceus), has been used in ancient Chinese medicine to support the immune system; as a tonic for the liver, kidneys, spleen and lungs; and to stimulate overall vitality. The polysaccharides present in Astragalus demonstrate immunopotentiating, antioxidant, and other health-related effects.

Cistus incanus, from a Mediterranean shrub, is commonly referred to as the “Gray-haired Rock Rose”. The potential effects of Cistus incanus include immune support and antioxidant properties. Of particular interest is its apparent protective effect on the gastro-intestinal system. For more details, see

Brazilian Green Propolis is a sticky green resin that comes from Brazilian honeybees feeding largely on the pollen of a particular tree, Baccharis dracunculifolia DC, (family Asteraceae). The bees use the resin as a building material in their hives. Propolis possesses antioxidant and immune system supporting properties.

Stevia extract comes from another herb in the Asteraceae family, Stevia rabaudiana. It is primarily marketed as a dietary alternative to sugar because of its intense sweetness and lack of calories. Stevia, however, has many health benefits. Experiments have shown it can promote normal blood sugar metabolism by enhancing insulin secretion and lowering glucose levels. Its phenolic content provides antioxidant and immune system supporting effects. For more details, see

QuintessenceTM is a blend of five of BioPure’s herbal tinctures that work together to provide broad-spectrum immune system support. QuintessenceTM includes:

  • King of Bitters (Andrographis paniculata) has been used in traditional Chinese medicine for general immune system support.
  • Red Root (Ceanothus americanus) has been used by Native Americans and homeopathic practitioners as an astringent tonic to help reduce stagnation in the lymphatic system.
  • Stephania tetrandra is commonly used in traditional Chinese and Japanese medicine. Tetrandine is a well-known alkaloid found in the plant. Research demonstrates it has vasodilating and diuretic properties.
  • Japanese Knotweed (Polygonum cuspidatum) is a bamboo-like perennial. Among its bioactive ingredients is a stilbene compound called resveratrol, also found in grapes and wine, with antioxidant, anti-coagulant effects.
  • Sarsparilla (Smilax glabra Roxb) comes from a tropical climbing vine. Experiments have shown it can exert detoxification properties.

For more information on BioPure’s QuintessenceTM see:


Appalasamy S, Lo KY, Ch’ng SJ, Nornadia K, Othman AS, and Chan LK. Antimicrobial Activity of Artemisinin and Precursor Derived from In Vitro Plantlets of Artemisia annua L. BioMed Research International, Vol. 2014, Article ID 215872, 6 pages.

Attaguile G, Caruso A, Pennisi G, Savoca F. Gastroprotective effect of aqueous extract of Cistus incanus L. in rats. Pharmacol Res. 1995 Jan;31(1):29-32.

Banerjee A, Chakrabarty SB, Karmakar SR, Chakrabarty A, Biswas SJ, Haque S, Das D, Paul S, Mandal B, Naoual B, Belon P, Khuda-Bukhsh R. Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary Study. Evid Based Complement Alternat Med. 2010 Mar; 7(1): 129-136.

Bergner P. Immune – Lymphatics and antibiotics. The Healing Power of Echinacea and Goldenseal. Prima 1997.

Bhagya N and Chandrashekar KR. Tetrandrine–A molecule of wide bioactivity. Phytochemistry. 2016 May;125:5-13.

Bralley EE, Greenspan P, Hargrove JL, Wicker L and Hartle DK. Topical anti-inflammatory activity of Polygonum cuspidatum extract in the TPA model of mouse ear inflammation. Journal of Inflammation. 2008 Vol 5:1.

Coon JT, Ernst E. Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Med. 2004 Apr;70(4):293-8.

Fukuda T, Fukui M, Tanaka M, Senmaru T, Iwase H, Yamazaki M, Aoi W, Unui T, Nakamura N, and Marunaka Y. Effect of Brazilian green propolis in patients with type 2 diabetes: A double-blind randomized placebo-controlled study. Biomed Rep. 2015 May; 3(3): 355–360.

Gao Y, Su Y, Qu L, Xu S, Meng L, Cai SQ, Shou C. Mitochondrial apoptosis contributes to the anti-cancer effect of Smilax glabra Roxb. Toxicol Lett. 2011 Nov 30;207(2):112-20.

Gehm BD, McAndrews JM, Chien P-Y, and Jameson JL. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. Proc. Natl. Acad. Sci. USA. Vol. 94, pp. 14138–14143, December 1997 Physiology.

Guimarães NSS, Mello JC, Paiva JS, Bueno Paula CP, Berretta AA, Torquato RJ, Nantes IL, Rodrigues T. Baccharis dracunculifolia, the main source of green propolis, exhibits potent antioxidant activity and prevents oxidative mitochondrial damage. Food and Chemical Toxicology. Volume 50, Issues 3–4, March–April 2012, Pages 1091–1097.

Gupta E, Purwar S, Sundaram Shanty and Rai GK. Nutritional and therapeutic values of Stevia rebaudiana: A review. Journal of Medicinal Plants Research. December 10, 2013. Vol. 7(46), pp. 3343-3353.

Hao S and Zhaobao W. Effects on exercise endurance capacity and antioxidant properties of Astragalus membranaceus polysaccharides (APS). Journal of Medicinal Plants Research. Vol. 4(10), pp. 982-986, May 2010.

Inokuchi Y, Shimazawa M, Nakajima Y, Suemori S, Mishima S, and Hara H. Brazilian Green Propolis Protects against Retinal Damage In Vitro and In Vivo. Evid Based Complement Alternat Med. 2006 Mar; 3(1): 71–77.

Jayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide. Evid Based Complement Alternat Med. 2013.

Jiang J and Xu Q. Immunomodulatory activity of the aqueous extract from rhizome of Smilax glabra in the later phase of adjuvant-induced arthritis in rats. Journal of Ethnopharmacology. Volume 85, Issue 1, March 2003, Pages 53-59.

Lemos M, de Barros MP, Sousa JP, da Silva Filho AA, Bastos JK, de Andrade SF. Baccharis dracunculifolia, the main botanical source of Brazilian green propolis, displays antiulcer activity. J Pharm Pharmacol. 2007 Apr;59(4):603-8.

Li XC, Cai L, Wu CD. Antimicrobial compounds from Ceanothus americanus against oral pathogens. Phytochemistry. 1997 Sep;46(1):97-102.

Lima LD, Andrade SP, Campos PP, Barcelos LS, Soriani FM, Moura SA, Ferreira MA. Brazilian green propolis modulates inflammation, angiogenesis and fibrogenesis in intraperitoneal implant in mice. BMC Complement Altern Med. 2014 May 29;14:177.

Machado JL, Assuncão A, Silva M, Reis A, Costa G, Arruda D, Rocha B, Vaz M, Paes A, Guerra R, Berretta A, Nascimento F. Brazilian Green Propolis: Anti-Inflammatory Property by an Immunomodulatory Activity. Evidence-Based Complementary and Alternative Medicine. Vol 2012, Article ID 157652, 10 pages.

Mao X, Yu F, Wang N, Wu Y, Zou F, Wu K, Liu M, Ouyang J. Hypoglycemic effect of polysaccharide enriched extract of Astragalus membranaceus in diet induced insulin resistant C57BL/gJ mice and its potential mechanism. Phytomedicine 16 (2009) 416-425.

Mohan K and Robert J. Hepatoprotective effect of Stevia rebaudiana Bertoni leaf extract in CCl4-induced liver injury in albino rats. Medicinal and Aromatic Plant Science and Biotechnology 3 (1):59–61.

Nagalekshmi R, Menon A, Chandrasekharan DK, Nair CK. Hepatoprotective activity of Andrographis paniculata and Swertia chirayita. Food Chem Toxicol. 2011 Dec;49(12):3367-73.

Sa F, Gao JL, Fung KP, Zheng Y, Lee SM, Wang YT. Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines. Chem Biol Interact. 2008 Jan 10;171(1):1-14.

Shao BM, Xu W, Dai H, Tu P, Li Z, Gao XM. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. Biochem Biophys Res Commun. 2004 Aug 6;320(4):1103-11.

Shen YC, Chou CJ, Chiou WF and Chen CF. Anti-inflammatory effects of the partially purified extract of Radix Stephaniae tetrandrae: Comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions. Molecular Pharmacology. November 1, 2001, Vol. 60 No. 5:1083-1090.

Shivanna N, Naika M, Khanum F, Kaul VK. Antioxidant, anti-diabetic and renal protective properties of Stevia rebaudiana. Journal of Diabetes and Its Complications 27 (2013) 103–113.

Shukla S, Mehta A, Bajpai VK, Shukla S. In vitro antioxidant activity and total phenolic content of ethanolic leaf extract of Stevia rebaudiana Bert. Food and Chemical Toxicology. Volume 47, Issue 9, September 2009, Pages 2338–2343.

Sinclair S. Chinese Herbs: A Clinical Review of Astragalus, Ligusticum, and Schizandrae. 1998. Alternative Medicine Review, Vol 3, No 5, page 338-344.

Treede I, Braun A, Sparla R, Kuhnel M, Giese T, Turner JR, Anes E, Kulaksiz H, Füllekrug J, Stremmel W. Anti-inflammatory effects of phosphatidylcholine. J Biol Chem. 2007, 282 (37).

Wagh VD. Propolis: A Wonder Bees Product and Its Pharmacological Potentials. Adv Pharmacol Sci. 2013; 11 pages.

Yang Z, Ding J, Yang C, Gao Y, Li X, Chen X, Peng Y, Fang J, Xiao S. Immunomodulatory and anti-inflammatory properties of artesunate in experimental colitis. Curr Med Chem. 2012;19(26):4541-51.